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IC50 values from 72 h MTT assays.
| Cell line | Tumor Type | ROC-325 IC50 (μM) | HCQ IC50 (μM) |
|---|---|---|---|
| A498 | Renal | 4.9 | 52 |
| A549 | Lung | 11 | >75 |
| CFPAC-1 | Pancreas | 4.6 | >75 |
| COLO-205 | Colon | 5.4 | 51 |
| DLD-1 | Colon | 7.4 | >75 |
| IGROV-1 | Ovarian | 11 | >75 |
| MCF-7 | Breast | 8.2 | >75 |
| MiaPaCa-2 | Pancreas | 5.8 | >75 |
| NCI-H69 | Lung | 5.0 | 54 |
| PC-3 | Prostate | 11 | 58 |
| RL | NHL | 8.4 | 35 |
| UACC-62 | Melanoma | 6.0 | >75 |
