Fig 4. The GO and pathway analysis of modules and hubs obtained from STRING and Gephi.

(A) The nodes are PR-specific proteins arranged according to betweenness centrality and colored in different modules based on the fast unfolding clustering algorithm implemented in Gephi [25]. (B) The nodes are PS-specific proteins arranged according to betweenness centrality and colored in different modules. (C) The nodes are PR- and PS-specific hubs. GO terms and significant pathways related to the modules as well as significant pathways associated with hubs are listed according to Enrichr in each group (based on the KEGG and Reactome databases).