Figure 4.

Changes of TNF-α, IL-1β, and fractalkine levels in the spinal cords of rats of each group seven days postoperative. Compared with the CCI group, TNF-α (a), IL-1β (b), and fractalkine (c) levels were lower in the HBO group, suggesting that HBO therapy can inhibit the inflammation of NNP in the spinal cord of rats. Compared with the HBO group, TNF-α, IL-1β, and fractalkine levels were higher in the K3 group, suggesting that although the K3 group was subjected to the same HBO therapy, overexpression of kindlin-1 can reverse the anti-inflammatory role of HBO therapy. *p < 0.05, ns, p > 0.05. n = 4. CCI: chronic constriction injury; HBO: hyperbaric oxygen.