Table 3.
Association between elevated cardiac troponin and mortality in ICU patients with sepsis.
| Source/Authors | Study design; Patient Enrolment (ICU type) | No. of patients; Type | Positive Troponin (%) | Mortality (positive Troponin) (%) | Mortality (negative Troponin) (%) | P value |
|---|---|---|---|---|---|---|
| Spies et al. (1998)22 | Prospective; SICU | 26; early sepsis | 69 | 83 | 37 | 0.02 |
| Amman et al. (2003)6 | Retrospective; MICU | 51; SIRS/severe sepsis/ septic shock | 63 | 48 | 12 | 0.018 |
| Mehta et al. (2004)15 | Prospective; MICU | 37; septic shock | 43 | 56 | 24 | 0.04 |
| Scott et al. (2008)21 | Prospective; SICU | 66; severe sepsis/septic shock | 64 | 29 | 21 | 0.69 |
| Kalla et al. (2008)23 | Prospective; medical/ surgical patients, MICU | 159; bacteraemic patients | 43 | 38 | 20 | <.05 |
| Choon-ngarm and Partpisanu (2008)25 | Prospective; MICU | 40; septic shock | 42 | 100 | 48 | 0.001 |
| John et al. (2010)20 | Prospective sub-study; MICU and SICU | 598; severe sepsis | 75 | 32 | 14 | <.0001 |
| Tiruvoipati et al. (2012)24 | Retrospective; MICU | 293; severe sepsis | 56 | 36 | 15 | <.01 |
| Vasile et al. (2013)19 | Retrospective; MICU | 926; sepsis/severe sepsis/septic shock | 70 | 31 | 17 | <.0001 |
ICU: intensive care unit; MICU: medical intensive care unit; SICU: surgical intensive care unit; SIRS = systemic inflammatory response syndrome.