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. Author manuscript; available in PMC: 2017 Sep 11.
Published in final edited form as: Nat Rev Nephrol. 2016 Oct 31;12(12):738–753. doi: 10.1038/nrneph.2016.156

Figure 1. Nanoparticle composition and features.

Figure 1

a | Nanoparticles are composed of a core (payload) encapsulated in a protective layer. The surface can be modified to limit the interactions of the particle with its environment. b | Several parameters such as size, shape and surface modification contribute to the biological and physicochemical properties of nanoparticles. The investigation of such properties is crucial to achieve the translational application of nanomedicines for kidney disease therapy. PEG, polyethylene glycol; ScFv Fc, single chain variable fragment constant fragment.