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. Author manuscript; available in PMC: 2018 Jul 17.
Published in final edited form as: Chem Soc Rev. 2017 Jul 17;46(14):4218–4244. doi: 10.1039/c6cs00636a

Fig. 3.

Fig. 3

Schematic of clathrin-mediated endocytosis. The process is initiated by ligand recognition and then the formation of clathrin-coated pits. With the aid of clathrin triskelions, a hexagonal lattice is formed, inducing the invagination of the plasma membrane. Afterwards, dynamin (a scission protein) releases the vesicle into the cytoplasm, where decoating takes place.