Table 3.

Baseline Characteristics of Patients with Virologic Failure

Patient	Drug	Age, yr	BMI, kg/m2	Genotype	Previous treatment	HCV RNA, log10 IU/mL	ALT, U/L	Cirrhosis	Undetectable HCV RNA, wk*	Response
1	DCV and ASV	38	26.2	1b	Naïve	6.4	32	No	4	Breakthrough without RAVs
2	DCV and ASV	45	21.6	1b	Nonresponse	5.8	37	No	4	Breakthrough with RAVs (L31M, Y93H)

BMI, body mass index; HCV, hepatitis C virus; ALT, alanine aminotransferase; DCV, daclatasvir; ASV, asunaprevir; RAVs, resistance-associated variants.

^*The lower limit of detection for the HCV RNA test is 15 IU/mL.