Table 3.
SIR of Second Primary Pancreatic Cancer after Colorectal Cancer, Stratified by Age
| Age at initial diagnosis | Observed no.* | Expected no.† | SIR | 95% CI |
|---|---|---|---|---|
| Male sex, yr | ||||
| 45–54 | 152.21 | 8.70 | 17.50 | 14.72–20.27 |
| 55–64 | 163.00 | 26.54 | 6.14 | 5.20–7.08 |
| 65–74 | 364.63 | 58.49 | 6.23 | 5.59–6.87 |
| Total | 234.82 | 23.32 | 10.07 | 8.78–11.36 |
| Female sex, yr | ||||
| 45–54 | 0 | 4.18 | 0 | - |
| 55–64 | 272.11 | 13.44 | 20.25 | 17.84–22.65 |
| 65–74 | 655.74 | 36.4 | 18.01 | 16.64–19.39 |
| Total | 325.91 | 14.25 | 22.87 | 20.39–25.35 |
| All patients, yr | ||||
| 45–54 | 86.73 | 6.47 | 13.40 | 10.58–16.23 |
| 55–64 | 203.87 | 19.87 | 10.26 | 8.85–11.67 |
| 65–74 | 468.66 | 46.12 | 10.16 | 9.24–11.08 |
| Total | 269.60 | 18.68 | 14.44 | 12.71–16.16 |
SIR, standardized incidence ratio; CI, confidence interval.
*
The observed incidence of second primary pancreatic cancer (PC) in patients with colorectal cancer (CRC) was standardized using a population with CRC from the Korean Central Cancer Registry (KCCR) of the National Cancer Center;
†
The expected incidence rate of PC was obtained from the KCCR.