Table 6.

False-positive report probability values for associations between breast cancer risk and genotypes in stratified factors

Genotype	Stratified factors	Positive OR (95% CI)a	P-valueb	Prior probability
				0.25	0.1	0.01	0.001
rs217727
CT/CC	All subjects	1.25 (1.03–1.51)	0.023	0.06	0.161	0.678	0.955
TT/CC	All subjects	1.56 (1.15–2.09)	0.004	0.021	0.061	0.419	0.879
CT + TT/CC	All subjects	1.31 (1.09–1.57)	0.004	0.007	0.022	0.197	0.712
	ER+	1.34 (1.09–1.64)	0.004	0.015	0.045	0.341	0.84
	HER2−	1.4 (1.14–1.71)	0.001	0.004	0.012	0.114	0.565
	HR+ HER2−	1.45 (1.16–1.81)	0.001	0.005	0.015	0.141	0.623

Notes:

^aCrude OR;

^blogistic regression analysis for genotype-frequency distributions.

Abbreviations: CI, confidence interval; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; HR, hormone receptor; OR, odds ratio.