Table 1.
Characteristics of Patients and Primary Tumors in the 2 Study Arms
| Intent-to-Treat Sample | Treatment Received Sample | |||
|---|---|---|---|---|
| ALND arm N = 420 |
SLND only arm N = 436 |
ALND N = 388 |
SLND only N = 425 |
|
| Age, years | ||||
| median (min, max) | 56(24,92) | 54(25,90) | 56(24, 92) | 54(25, 90) |
| missing | 7 | 10 | 7 | 10 |
| Age, years | ||||
| ≤ 50, no. (%) | 135(32.7) | 160(37.6) | 124 (32.6) | 155 (37.4) |
| > 50, no. (%) | 278(67.3) | 266(62.4) | 257 (67.4) | 260 (62.6) |
| missing | 7 | 10 | 7 | 10 |
| Clinical T stage, no. (%) | ||||
| T1 | 284(67.9) | 303(70.6) | 259(67.1) | 296(70.5) |
| T2 | 134(32.1) | 126(29.4) | 127(32.9) | 124(29.5) |
| missing | 2 | 7 | 2 | 5 |
| Clinical tumor size, cm | ||||
| median (min, max) | 1.7(0.4,7.0) | 1.6(0.0,5.0) | 1.8 (0.4, 6.0) | 1.6 (0, 5.0) |
| missing | 6 | 14 | 6 | 12 |
| Receptor status, no. (%) | ||||
| ER+/PgR+ | 256(66.8) | 270(68.9) | 273(66.8) | 264(68.9) |
| ER+/PgR− | 61(15.9) | 54(13.8) | 54(15.2) | 52(13.6) |
| ER−/PgR+ | 3(0.8) | 4(1.0) | 3(0.8) | 4(1.0) |
| ER−/PgR− | 63(16.5) | 64(16.3) | 61(17.2) | 63(16.5) |
| missing | 37 | 44 | 33 | 42 |
| Estrogen Receptor, no. (%) | ||||
| ER+ | 327(83.0) | 332(83.0) | 301(82.2) | 323(82.8) |
| ER− | 67(17.0) | 68(17.0) | 65(17.8) | 67(17.2) |
| missing | 26 | 36 | 22 | 35 |
| Progesterone Receptor, no. (%) | ||||
| PR+ | 260(67.7) | 274(69.9) | 241(67.7) | 268(70.0) |
| PR− | 124(32.3) | 118(30.1) | 115(32.3) | 115(30.0) |
| missing | 36 | 44 | 32 | 42 |
| LVI*, no. (%) | ||||
| Yes | 129(40.6) | 113(35.2) | 124(41.7) | 111(35.6) |
| No | 189(59.4) | 208(64.8) | 173(58.3) | 201(64.4) |
| missing | 102 | 115 | 91 | 113 |
| Modified Bloom-Richardson score, no (%) | ||||
| I | 71(22.0) | 81(25.6) | 64(21.3) | 80(26.0) |
| II | 158(48.9) | 148(46.8) | 147(49.0) | 142(46.3) |
| III | 94(29.1) | 87(27.5) | 89(29.7) | 85(27.7) |
| missing/unknown | 97 | 120 | 88 | 118 |
| Tumor type, no. (%) | ||||
| Infiltrating ductal | 344(82.7) | 356(84.0) | 317(82.1) | 347(84.0) |
| Infiltrating lobular | 27(6.5) | 36(8.5) | 25(6.5) | 35(8.5) |
| Other | 45(10.8) | 32(7.5) | 44(11.4) | 31(7.5) |
| missing | 4 | 12 | 2 | 12 |
*
LVI, Lymphovascular invasion