Table 3.
Univariable and multivariable associations of prognostic factors with locoregional recurrence for the intent-to-treat sample.
| Univariable p |
HR (CI) (univariable) |
Multivariable p (all variables) |
HR (CI) (all variables) |
||
|---|---|---|---|---|---|
| ER Status | |||||
| Negative | 0.0002 | 0.229 (0.106, 0.496) | 0.6244 | 0.707 (0.176, 2.837) | |
| Positive | |||||
| PR Status | |||||
| Negative | 0.0207 | 0.410 (0.193, 0.873) | 0.3724 | 0.501 (0.110, 2.289) | |
| Positive | |||||
| Pathologic Tumor Size | |||||
| Path tum size | 0.0012 | 1.242 (1.090, 1.416) | 0.4686 | 1.085 (0.870, 1.353) | |
| Lymphovascular Invasion | |||||
| Yes | 0.1832 | 0.559 (0.237, 1.316) | 0.4405 | 0.652 (0.219, 1.935) | |
| No | |||||
| Histologic Type | |||||
| Ductal | --- | --- | --- | --- | |
| Lobular | 0.9848 | 0.000 (0.000, .) | 0.9952 | 0.000 (0.000, .) | |
| Other | 0.3060 | 0.353 (0.048, 2.593) | 0.9953 | 0.000 (0.000, .) | |
| Sentinel Node Met Size | |||||
| Micro | 0.3080 | 0.670 (0.311, 1.446) | 0.4255 | 0.620 (0.191, 2.010) | |
| Macro | |||||
| # Positive Total LN | |||||
| 0 | 0.5335 | 1.160 (0.727, 1.852) | 0.2948 | 1.505 (0.700, 3.234) | |
| 1 | |||||
| 2 | |||||
| 3 or more | |||||
| Modified Bloom-Richardson Score | |||||
| I | 0.0002 | 6.105 (2.385, 15.622) | 0.0258 | 3.536 (1.165, 10.733) | |
| II | |||||
| III | |||||
| Adjuvant Systemic Therapy | |||||
| No | 0.1687 | 0.583 (0.270, 1,257) | 0.1281 | 0.429 (0.144, 1.276) | |
| Yes | |||||
| Age | |||||
| ≤50 | 0.0421 | 0.468 (0.225, 0.973) | 0.0260 | 0.285 (0.095, 0.861) | |
| >50 | |||||
| Arm | |||||
| ALND | 0.2802 | 0.666 (0.318, 1.394) | 0.7411 | 0.825 (0.263, 2.586) | |
| SLND only | |||||