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. 2017 Aug 23;40(4):1019–1028. doi: 10.3892/ijmm.2017.3105

Table I.

Genes associated with specific GO terms (angiogenesis, cell proliferation, adhesion, inflammatory response, apoptosis and hypoxia) in DVT. Genes related to endothelial cells are marked in bold.

Specific Go terms Upregulated genes Downregulated genes
Angiogenesis - APOLD1, CALCRL, KLF4, DLL1, CXCL12, EMP2, GATA2, VEGFB
Cell proliferation PTH, KCNH1, ITGA2 ARC, CALCRL, CAV2, CHP2, CXCL12, DLL1, EFEMP1, EMP2, GAS6, GATA2, KLF4, NACC2, NDRG4, PBX1, PPARG, PTHLH, RERG, SPRY2, TNFRSF11B, VEGFB, WFDC1, WISP2, ZFP36L1
Adhesion ITGA2 PPAP2B, HSPA2, GAS6, ZFP36L1, CXCL12, JAM2, KLF4, EMP2, FLRT3, WISP2, DLL1, CAV2, HAS1, ITGA, RND3, CNTNAP1
Inflammatory response ITGA2 PPARG, CALCRL, WFDC1, STK39, TNFRSF11B, IL17RE
Apoptosis PTH ARC, HSPA2, GAS6, TNFRSF11B, NACC2, PPARG, SPRY2, CXCL12, VEGFB, GULP1, KLF4, ZFP36L1, DLL1, STK39
Hypoxia ITGA2 APOLD1, CYGB, ARC, CXCL12

GO, Gene Ontology.