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. 2017 Aug 11;40(4):1185–1193. doi: 10.3892/ijmm.2017.3098

Figure 8.

Figure 8

Effect of AG490 and valsartan on protein expression and Janus kinase-2/signal transducers and activator of transcription 3 (JAK2/STAT3) activation. (A and B) The activation of JAK2 and STAT3 was measured by western blot analysis. (C and D) The protein expression levels of CXCL9 and apoptosis-associated proteins were measured by western blot analysis. lane a, control; lane b, AGE; lane c, AGE + AG490; lane d, AGE + Valsartan. ***P<0.001 vs. control; #P<0.05, ##P<0.01 and ###P<0.001 vs. advanced glycation end products (AGEs).