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. 2017 May 7;8(34):56417–56427. doi: 10.18632/oncotarget.17662

Figure 4. Western Blot analysis of miR-148a-3p effects on endogenous SOS1/2 protein levels in B cell lines.

Figure 4

(A) Transfection of miR-148a-3p using miRNA mimics causes significantly reduced SOS1 expression in BJAB (63%, P = 0.009) and U2932 (72%, P = 0.026) cells. (B) Transfection of miR-148a-3p mimics results in significantly decreased SOS2 protein levels in BJAB (67%, P = 0.04) and DG-75 (72%, P = 0.0006) cells. The expression of SOS1 in DG-75 and SOS2 in U2932 cells was considered as too low for further downregulation, as shown in Supplementary Figure 3.