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. 2017 May 7;8(34):56417–56427. doi: 10.18632/oncotarget.17662

Figure 5. Western Blot analysis of miR-148a effects on the activation of ERK1/2 in HEK-293T cells.

Figure 5

Measurement of activated (phosphorylated) ERK1/2 as a downstream effect of decreased SOS1/2 protein levels due to overexpression of miR-148a results in significantly reduced phosphorylation of ERK1/p44 to 60% and ERK2/p42 to 61% (P = 0.02 each).