Figure 2. Hierarchical clustering of differentially expressed miRNAs in NB cell lines.

Differential expression analysis between ALK+ and ALK- categories was carried out using Student’s t-test (unpaired, two-tailed, unequal variance). SKNBE2 cell line was removed from the analysis for low quality hybridization. 71 miRNAs showed raw p-value < 0.05. miR-424-5p and miR-503-5p are highlighted with a red font.