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. 2017 Apr 11;8(34):56518–56532. doi: 10.18632/oncotarget.17033

Figure 4. Validation of candidate miRNAs.

Figure 4

(A) Venn diagram representing the number of miRNAs that were found to be down-regulated in ALK+ group (or up-regulated in ALK- group). Filtering criteria for prioritizing miRNAs for validation and functional analyses are described in the results. (B) Validation analysis of miRNAs expression was performed by qPCR and data were box-plotted using BoxPlotR. p-value < 0.05 (*); p-value < 0.01 (**). (C) miR-424-5p/ALK 3′-UTR alignment as predicted by MicroRNA.org. Sequence starts at 321 bp of ALK 3′-UTR. mirSVR score:-0.9220; PhastCons score: 0.5638.