Table 4. Multivariate analysis for pCR predictive parameters.

Variable	pCR (n)	Non-pCR (n)	P value	Hazard ratio	95% CI
Menstrual status
Premenopause	13	30	0.191	2.391	0.647–8.831
Postmenopause	17	28
Age
≤ 35 years	4	9	0.131	4.168	0.655–26.532
> 35years	26	49
BMI
≤ 25	20	34	0.432	1.558	0.516–4.708
> 25	10	24
Laterality
Left	14	36	0.121	2.035	0.830–4.993
Right	16	22
Family history
Yes	3	3	0.086	0.441	0.173–1.123
No	27	55
Cycles
< 4	4	8	0.897	1.102	0.253–4.806
≥ 4	26	50
HR status
Negative	22	22	< 0.001	5.587	2.257–13.889
Positive	8	36
Ki-67
High (> 30%)	19	20	0.003	4.130	1.607–10.610
Low (≤ 30%)	11	38
T stage
T1–2	24	49	0.780	0.850	0.272–2.659
T3–4	6	9

pCR: pathologic complete response; BMI: body mass index; HR: hormone receptor; T: tumor; CI: confidence interval.