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. 2017 May 23;8(34):56698–56713. doi: 10.18632/oncotarget.18082

Table 4. Tumour initiation frequency is lower in xenograft cells treated with a combination of AKT and mTOR inhibitor.

Number of inoculated cells 10 000 cells 1000 cells 100 cells 10 cells 1 cell Tumour initiation frequency(95% CI)
Treatment
0.2% DMSO 2/2 2/2 2/2 1/2 0/2 16.6 (98.9-3.16)
10 γM AZD7328 2/2 2/2 2/2 0/2 0/2 43.8 (201.1-9.84)
10 γM KU-0063794 2/2 2/2 2/2 1/2 0/2 16.6 (98.9-3.16)
10 +10 combination 2/2 2/2 0/2 0/2 0/2 434.6 (2008.4-94.36)