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. 2017 Jun 16;8(34):57012–57023. doi: 10.18632/oncotarget.18505

Figure 2. MiR-107-5p inhibits cell proliferation and migration in NSCLC cells.

Figure 2

(A) The expression of miR-107-5p was measured by qRT-PCR in A549 and HCC827 cells 48 h after transfection with NC (negative control) or miR-107-5p mimic. (B-C) A549 and HCC827 cells were transfected with NC or miR-107-5p mimic, and cell proliferation was determined by CCK-8. (D) Colony formation assay was performed in A549 and HCC827 cells after transfected with NC or miR-107-5p mimic. (E) Wound-healing assays were performed to evaluate the effect of miR-107-5p on the migratory ability in the A549 and HCC827 lines. Photos of the cells were taken at 0 and 24 h, the relative migration length was from three randomly selected locations. All experiments were repeated in triplicate (*P < 0.05, **P < 0.01, ***P < 0.001).