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. 2017 Jun 16;8(34):57012–57023. doi: 10.18632/oncotarget.18505

Figure 6. Overexpression of miR-107 inhibits tumor growth.

Figure 6

(A) MiR-107-stably-overexpressing A549 cells (pLenti-miR-107) and control (pLenti) were injected into nude mice. Each group comprised 5 mice. Tumor sizes were measured every week and growth curves were generated. (B) Mice were sacrificed after 7 weeks and tumor weights were measured. (C) Tumor images were displayed. (D) The expression of miR-107 was detected by qRT-PCR in the mouse tumor tissues induced by NC and miR-107-stably-overexpressing A549 cells. (E) The expression of Ki67, EGFR in tumor tissues was measured by immunohistochemistry (*P < 0.05, **P < 0.01, ***P < 0.001).