Table 3. Comparison of in vivo and ex vivo Ab uptake by tumor at 96 h in different Ab-F groups.
Ab-F | In vivo (% ID/g ± SEM) | Ex vivo (% ID/g ± SEM) |
---|---|---|
BODIPY630 | n.d. | 5 ± 1 |
VT645 | 34 ± 6 | 31 ± 3 |
AF647 | 24 ± 2 | 23 ± 3 |
VT680 | 26 ± 5 | 15 ± 3 |
AF680 | 18 ± 5 | 12 ± 3 |
AF750 | 24 ± 6 | 24 ± 5 |
IR800Dye | 17 ± 5 | 19 ± 5 |
The Ab uptake was calculated from the in vivo and ex vivo images as %ID/g using the torso (whole-body) FMT signal at 5 min as the total dose.