Table 1. Baseline demographic and clinical characteristics of the study patients.
| Characteristic | All patients | High-grade glioma, n=43 | Low grade glioma, n=20 | Meningioma, n=89 | Significance |
|---|---|---|---|---|---|
| Age Mean ± SD, Median [IQR] <50 years, n (%) ≥50 years, n (%) |
56.9±14.7, 59 [21] 47 (31%) 105 (69%) |
58.9±13.8 59 [19] 9 (21%) 34 (79%) |
39.0±13.4 37 [18] 16 (80%) 4 (30%) |
59.9±12.5 61 [19] 22 (25%) 67 (75%) |
X2=27.24, p<0.001 X2=26.17, p<0.001 |
| Gender, n (%) Men Women |
47 (31%) 105 (69%) |
18 (42%) 25 (58%) |
11 (55%) 9 (45%) |
18 (20%) 71 (80%) |
X2=12.61, p=0.002 |
| Marital status, n (%) With partner Single |
108 (75%) 37 (25%) |
32 (80%) 8 (20%) |
14 (78%) 4 (22%) |
62 (71%) 25 (29%) |
X2=2.76, p=0.60 |
| Education, n (%) Not graduated from high school Graduated from high school Some university education Graduated from university |
19 (13%) 55 (38%) 40 (28%) 28 (19%) |
7 (18%) 13 (33%) 13 (33%) 7 (18%) |
1 (6%) 6 (33%) 7 (39%) 4 (22%) |
11 (13%) 36 (42%) 20 (23%) 17 (20%) |
X2=10.32, p=0.41 |
| History of depression | 10 (7%) | 1 (2%) | 0 | 9 (10%) | X2=4.384; p=0.11 |
| Current use of psychotropic medication | 14 (9%) | 2 (5%) | 3 (16%) | 9 (10%) | X2=2.126; p=0.35 |
| Barthel index, n (%) Score <100 |
41 (27%) |
18 (43%) |
1 (6%) |
22 (26%) |
X2=9.33, p=0.009 |
| Recurrent tumor, n (%) | 24 (16%) | 10 (25%) | 2 (10%) | 12 (14%) | X2=2.98, p=0.2 |
| Extent of resection, n (%) Complete Incomplete or biopsy |
130 (86%) 22 (14%) |
35 (88%) 5 (12%) |
17 (85%) 3 (15%) |
78 (93%) 6 (7%) |
X2=1.62, p=0.4 |
| Adjuvant therapy, n (%) Yes Radiotherapy Chemotherapy |
47 (31%) 44 (29%) 19 (13%) |
34 (79%) 33 (77%) 16 (37%) |
7 (35%) 7 (35%) 1 (5%) |
6 (7%) 4 (5%) 2 (2%) |
X2=71.19, p<0.001 X2=73.99, p<0.001 X2=33.59, p<0.001 |
| HADS-Depression score, n (%) ≤ 7 8 – 10 ≥ 11 |
110 (73%) 22 (15%) 19 (12%) |
27 (63%) 7 (16%) 9 (21%) |
17 (90%) 1 (5%) 1 (5%) |
66 (74%) 14 (16%) 9 (10%) |
X2 = 6.259; p=0.18 |
| HADS-Anxiety score, n (%) ≤ 7 8 – 10 ≥ 11 |
96 (64%) 32 (21%) 23 (15%) |
29 (67%) 8 (19%) 6 (14%) |
12 (63%) 5 (26%) 2 (11%) |
55 (62%) 19 (21%) 15 (17%) |
X2 = 0.994; p=0.91 |
HADS, Hospital Anxiety and Depression Scale; IQR, interquartile range