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. 2017 Mar 17;8(34):57594–57604. doi: 10.18632/oncotarget.16338

Table 3. Prediction of occurrence of AAD with Cox proportional hazard regression model.

Univariate Multivariate
HR 95% CI p-value HR 95% CI p-value
Gender
Female 1.00 1.00
Male 2.68 1.37 - 5.25 0.0041 2.75 1.34 - 5.64 0.0058
Age
18-39 1.00 1.00
40-65 10.89 1.48 - 80.38 0.0192 8.65 1.13 - 66.01 0.0375
>65 39.67 5.24 - 300.29 0.0004 20.25 2.49 - 164.87 0.0049
Urbanization level
1 (highest) 1.00 1.00
2 0.91 0.43 - 1.94 0.814 0.94 0.44 - 2.02 0.8775
3 2.61 1.21 - 5.63 0.0145 2.33 1.04 - 5.22 0.0403
4 (lowest) 0.55 0.07 - 4.23 0.5687 0.41 0.05 - 3.28 0.4033
Income (NTD per month)
0 1.00 1.00
1-15,840 0.63 0.23 - 1.75 0.3781 0.62 0.22 - 1.73 0.3625
15,841-25,000 0.57 0.26 - 1.25 0.1587 0.49 0.21 - 1.14 0.0959
>25,000 0.48 0.2 - 1.19 0.1127 0.5 0.18 - 1.38 0.1807
ADPKD
No 1.00 1.00
Yes 9.18 4.97 - 16.96 <.0001 3.91 1.53 - 10 0.0043
Medical diseases
Hypertension 15.01 5.35 - 42.11 <.0001 6.42 2.09 - 19.71 0.0012
Diabetes mellitus 0.57 0.2 - 1.6 0.2875 0.29 0.1 - 0.84 0.0219
Dyslipidemia 1.27 0.65 - 2.49 0.4892 0.83 0.41 - 1.67 0.5918
Gout 2.49 1.27 - 4.87 0.008 0.77 0.37 - 1.6 0.4894
Atrial fibrillation 1.46 0.2 - 10.63 0.7082 0.32 0.04 - 2.41 0.2665
Ischemic heart disease 3.25 1.75 - 6.06 0.0002 1.1 0.54 - 2.22 0.7982
Heart failure 6.29 3.09 - 12.84 <.0001 2.1 0.94 - 4.72 0.0711
Cerebrovascular accident 3.48 1.7 - 7.09 0.0006 0.87 0.35 - 2.17 0.7713
Hemorrhagic stroke 6.49 2.31 - 18.2 0.0004 1.98 0.54 - 7.36 0.3057
Peripheral vascular disease 2.02 0.62 - 6.54 0.2417 0.82 0.25 - 2.71 0.7451
Chronic kidney disease 9.63 5.17 - 17.93 <.0001 1.57 0.61 - 4.03 0.3509
Malignancy of kidney or bladder 3.5 0.48 - 25.48 0.2157 0.77 0.1 - 5.78 0.7981

Abbreviations: AAD, aortic aneurysm/dissection; HR, hazard ratio; CI, confidence interval; NTD, New Taiwan dollars; ADPKD, autosomal dominant polycystic kidney disease.