Table 2. Main results for meta-analysis between PLK1 and clinicopathological features in breast cancer.
Clinicopathological features | Study(n) | Pooled OR(95%CIs) | z | P | Heterogeneity | Publication bias | |||
---|---|---|---|---|---|---|---|---|---|
I2 | P | Estimated method | z | P | |||||
Age | 7 | 1.018(0.795,1.303) | 0.14 | 0.888 | 0.00% | 0.670 | Fixed model | 0.90 | 0.368 |
Tumor size | 7 | 1.703(1.315,2.205) | 4.04 | <0.001 | 30.10% | 0.198 | Fixed model | 0.90 | 0.368 |
Grading | 7 | 6.028(2.639,13.772) | 4.26 | <0.001 | 78.90% | <0.001 | Ramdon model | 0.90 | 0.368 |
Lymph node | 7 | 1.524(1.192,1.950) | 3.35 | 0.001 | 43.20% | 0.090 | Fixed model | 0.62 | 0.536 |
Tumor type | 3 | 0.215(0.083 ,0.557) | 3.17 | 0.002 | 0.00% | 0.609 | Fixed model | 0.00 | 1.000 |
ER status | 7 | 0.392(0.202,0.762) | 2.76 | 0.006 | 73.30% | 0.001 | Ramdon model | 1.50 | 1.330 |
PR status | 5 | 0.560(0.229,1.364) | 1.28 | 0.202 | 76.90% | 0.002 | Ramdon model | −0.24 | 1.000 |
P53 | 3 | 6.663(4.249,10.448) | 8.26 | <0.001 | 22.60% | 0.275 | Fixed model | 0.00 | 1.000 |
HER2 | 4 | 1.447(0.795,2.633) | 1.21 | 0.226 | 0.00% | 0.729 | Fixed model | −0.34 | 1.000 |