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. 2017 Apr 20;8(34):57723–57732. doi: 10.18632/oncotarget.17301

Table 3. Summary table of HRs and their 95% CI for survival analysis.

Survival HR(95%CIs) Significance Method Publication bias
OS
Weichert2005 2.010(0.880,4.590) NS Survival curve
Loddo2009 3.460(1.370,8.710) Poor Univariate
Li 2011 4.760(1.341,6.123) Poor Multivariate
King 2012 3.890(1.820,8.320) Poor Survival curve
Combined HR 3.438(2.293,5.154) z = 5.98, P < 0.001; I2 = 0%, P = 0.487 Fixed-effects model z = 1.02, P = 0.308
CSS
Miller2005 1.739(1.014,2.985) Poor Original data
Ali 2012 2.600(1.300,5.200) Poor Univariate
Donizy 2016 6.130(2.300,16.330) Poor Multivariate
Combined HR 2.414(1.633,3.567) z = 4.42, P < 0.001; I2 = 59.50%, P = 0.085 Fixed-effects model z = 1.04, P = 0.296
DFS
Ivshina 2006 1.736(1.378,2.646) Poor Original data
Loddo2009 3.310(1.570,6.970) Poor Multivariate
Maire 2012 3.410(1.030,11.260) Poor Univariate
King 2013 6.050(2.130,17.170) Poor Survival curve
Donizy 2016 3.620(1.500,8.740) Poor Survival curve
Combined HR 2.261(1.732,2.951) z = 6.00, P < 0.001; I2 = 52.9%, P = 0.075 Fixed-effects model z = 0.73, P = 0.462