Table 3. Summary table of HRs and their 95% CI for survival analysis.
Survival | HR(95%CIs) | Significance | Method | Publication bias |
---|---|---|---|---|
OS | ||||
Weichert2005 | 2.010(0.880,4.590) | NS | Survival curve | |
Loddo2009 | 3.460(1.370,8.710) | Poor | Univariate | |
Li 2011 | 4.760(1.341,6.123) | Poor | Multivariate | |
King 2012 | 3.890(1.820,8.320) | Poor | Survival curve | |
Combined HR | 3.438(2.293,5.154) | z = 5.98, P < 0.001; I2 = 0%, P = 0.487 | Fixed-effects model | z = 1.02, P = 0.308 |
CSS | ||||
Miller2005 | 1.739(1.014,2.985) | Poor | Original data | |
Ali 2012 | 2.600(1.300,5.200) | Poor | Univariate | |
Donizy 2016 | 6.130(2.300,16.330) | Poor | Multivariate | |
Combined HR | 2.414(1.633,3.567) | z = 4.42, P < 0.001; I2 = 59.50%, P = 0.085 | Fixed-effects model | z = 1.04, P = 0.296 |
DFS | ||||
Ivshina 2006 | 1.736(1.378,2.646) | Poor | Original data | |
Loddo2009 | 3.310(1.570,6.970) | Poor | Multivariate | |
Maire 2012 | 3.410(1.030,11.260) | Poor | Univariate | |
King 2013 | 6.050(2.130,17.170) | Poor | Survival curve | |
Donizy 2016 | 3.620(1.500,8.740) | Poor | Survival curve | |
Combined HR | 2.261(1.732,2.951) | z = 6.00, P < 0.001; I2 = 52.9%, P = 0.075 | Fixed-effects model | z = 0.73, P = 0.462 |