Table 3. A list of AR-signature genes that have AR-binding signals in their 5 kb promoter regions using ChIP-seq data.
Gene | AR average | C1orf64 CC | p value | Datasets |
---|---|---|---|---|
*C1orf64 | 165 | 1 | <0.001 | BC Cell lines |
*SIDT1 | 133 | 0.667 | <0.001 | TCGA Breast |
*F7 | 58 | 0.678 | <0.001 | BC Cell lines |
PATZ1 | 38 | >0.05 | TCGA Breast | |
*RHOH | 116 | 0.629 | <0.001 | BC Cell lines |
CCDC125 | 267 | >0.05 | TCGA Breast | |
TBC1D30 | 119 | >0.05 | Bos Breast | |
*SPDEF | 51 | 0.734 | <0.001 | BC Cell lines |
*DOPEY2 | 230 | 0.693 | <0.001 | BC Cell lines |
*RHOB | 216 | 0.677 | <0.001 | BC Cell lines |
SLCO2A1 | 30 | >0.05 | BC Cell lines | |
*FOXA1 | 174 | 0.721 | <0.001 | BC Cell lines |
*SLC9A2 | 60 | 0.809 | <0.001 | BC Cell lines |
PYGO1 | 27 | >0.05 | BC Cell lines | |
*TTC6 | 174 | 0.631 | <0.001 | BC Cell lines |
*CREB3L4 | 27 | 0.775 | <0.001 | BC Cell lines |
*SLC16A6 | 839 | 0.505 | 0.001 | BC Cell lines |
*KIAA1324 | 46 | 0.727 | <0.001 | BC Cell lines |
*DEGS2 | 498 | 0.665 | <0.001 | BC Cell lines |
TRIL | 45 | >0.05 | TCGA Breast | |
DALRD3 | 293 | NA | ||
*UMODL1 | 42 | 0.675 | <0.001 | BC Cell lines |
GSE1 | 19 | >0.05 | TCGA Breast | |
AMBP | 333 | >0.05 | BC Cell lines | |
*ZG16B | 107 | 0.577 | <0.001 | TCGA Breast |
*CRAT | 654 | 0.42 | 0.009 | BC Cell lines |
MVK | 46 | NA | ||
CACFD1 | 120 | NA | ||
*SLC9A3R1 | 101 | 0.659 | <0.001 | BC Cell lines |
*ATP8A1 | 34 | 0.664 | <0.001 | BC Cell lines |
*PIM1 | 44 | −0.632 | <0.001 | BC Cell lines |
Average ChIP-seq signal for AR binding, correlation coefficient (CC) between the expression of each signature gene and C1orf64, p value for each CC, and the source of data for CC analysis are shown. BC: breast cancer, NA: not available. Asterisks depict the AR-signature genes that have a detectable AR-binding signal using ChIP-seq and a significant correlation (p<0.01) with C1orf64 expression in breast cancer.