Table 1.
Immune cells | Localization | Prognostic impact | References |
---|---|---|---|
Conventional CD4+ and CD8+ T lymphocytes | Primary tumor | Good and Bad | 32,35,36,87 |
Metastases | Good and Bad | 29,42 | |
Regulatory T cells | Primary tumor | Bad/No impact | 37-39,47 |
Metastases | Bad/No impact | 29,37,39-42 | |
B lymphocytes | Primary tumor | Good | 77,78 |
Metastases | Good | 29 | |
Plasmocytes | Primary tumor | Bad | 79 |
Metastases | Good | 29 | |
NK cells | Primary tumor | Good | 96 |
Metastases | Good | 97,98 | |
MDSC | Primary tumor | Bad | 83 |
Metastases | Bad | 42,83 | |
Plasmacytoid DC | Primary tumor | Bad | 35,82 |
Metastases | Bad | 81 | |
DC | Primary tumor | Good | 35,87 |
Metastases | Good/No impact | 29,89 | |
Macrophages | Primary tumor | Bad | 88 |
Metastases | Bad/No impact | 29,89 | |
Neutrophils | Primary tumor | Bad | 35 |
Mastocytes | Primary tumor | Bad | 80 |