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. 2017 Mar 7;6(8):e1299303. doi: 10.1080/2162402X.2017.1299303

Table 1.

Melanoma prognosis depends on immune cell composition and localization.

Immune cells Localization Prognostic impact References
Conventional CD4+ and CD8+ T lymphocytes Primary tumor Good and Bad 32,35,36,87
  Metastases Good and Bad 29,42
Regulatory T cells Primary tumor Bad/No impact 37-39,47
  Metastases Bad/No impact 29,37,39-42
B lymphocytes Primary tumor Good 77,78
  Metastases Good 29
Plasmocytes Primary tumor Bad 79
  Metastases Good 29
NK cells Primary tumor Good 96
  Metastases Good 97,98
MDSC Primary tumor Bad 83
  Metastases Bad 42,83
Plasmacytoid DC Primary tumor Bad 35,82
  Metastases Bad 81
DC Primary tumor Good 35,87
  Metastases Good/No impact 29,89
Macrophages Primary tumor Bad 88
  Metastases Bad/No impact 29,89
Neutrophils Primary tumor Bad 35
Mastocytes Primary tumor Bad 80