Figure 5.

In vitro tumor growth restraining activity by DEPDC1#5 peptide-stimulated CTLs. The figure reports the inhibition of MDA-MB-231 outgrowth by DEPDC1#5 peptide-stimulated T cells after 4 weeks of culture. MDA-MB-231 cultured alone or in presence of control CTL (Ctrl-CTL), and NIH 3T3 cells alone or co-cultured with DEPDC1#5 peptide-stimulated CTL were used as negative controls. Results are expressed as percentage of target cell growth inhibition and the numbers above each bar refer to the target:CTL ratio (n = 3 healthy donors).