Table 2.
Clinical Characteristics
| Variable | Sertraline n=31 |
Placebo n=31 |
P-valuea |
|---|---|---|---|
| History of depression | |||
| No history of depression | 11 (37%) | 11 (37%) | .092 |
| Pre-injury history of depression, not at injury | 17 (57%) | 11 (37%) | |
| Pre-injury history of depression, depressed at injury | 2 (7%) | 8 (27%) | |
| Unknown | 1 | 1 | |
| History of posttraumatic stress disorder | |||
| No | 27 (90%) | 28 (90%) | 1.0 |
| Yes | 3 (10%) | 3 (10%) | |
| Unknown | 1 | 0 | |
| History of other mental health diagnosis b | |||
| No | 27 (87%) | 28 (90%) | 1.0 |
| Yes | 4 (13%) | 3 (10%) | |
| History of alcohol or drug dependence | |||
| No | 10 (32%) | 9 (29%) | 1.0 |
| Yes | 21 (68%) | 22 (71%) | |
| Current anxiety disorder | |||
| No | 9 (29%) | 11 (35%) | .79 |
| Yes | 22 (71%) | 20 (65%) | |
| Concurrent counseling during year following TBI | |||
| No | 18 (75%) | 24 (83%) | .52 |
| Yes | 6 (25%) | 5 (17%) | |
| Unknown | 7 | 2 |
a
Statistical significance by Fisher’s exact test
b
Other mental health diagnoses included bipolar disorder or manic depression, generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, any phobia, schizophrenia, schizoaffective disorder, or any psychotic disorder.