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. Author manuscript; available in PMC: 2018 Oct 10.
Published in final edited form as: J Control Release. 2017 Mar 11;263:120–131. doi: 10.1016/j.jconrel.2017.03.017

Figure 2. Activation of microbubbles with MRgFUS opens the BTB in F98 gliomas, as well as the BBB in surrounding brain tissue.

Figure 2

Representative contrast enhanced T1-weighted MR images of F98 glioma before (Pre-FUS) and after (Post-FUS) MRgFUS activation of microbubbles using a 9 spot grid pattern. BTB/BBB opening is indicated by increases in both the intensity and area of contrast enhancement.