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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Neurogastroenterol Motil. 2017 Jul 28;29(10):1–10. doi: 10.1111/nmo.13172

Figure 3.

Figure 3

Effect of ICC on sample size requirements. As reproducibility decreases, i.e. ICC is lower, a larger sample size is required to detect all 3 effect sizes with 80% power at an α level of 0.05. For example, when the ICC is 0.6, a sample size of 1.5*25= x, 1.5*50= x, and 1.5*100= x is sufficient to detect strong, medium, and weak effects, respectively.