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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Comp Biochem Physiol B Biochem Mol Biol. 2017 Jul 21;213:55–80. doi: 10.1016/j.cbpb.2017.07.001

Fig. 4.

Fig. 4

The sequential reactions and metabolic relationships of dihydrofolate reductase and thymidylate synthase for the cycle of dTMP synthesis. DHF, dihydrofolate; THF, tetrahydrofolate. (After Voet and Voet, 2004).