Table 4.

Summary Statistics for Mutation Analysis.

	Syndromic	Nonsyndromic	Odds ratio (CI)	P Value
N number	10	10
Males, Females	6, 4	5, 5
Age (mean ± SD)	33 ± 14	44 ± 16		p = 0.16
% of Patients with indels or nonsense mutations	70 (7/10)	30 (3/10)	6.4 (0.5, 128)	p = 0.09†
% of Alleles with indels or nonsense mutations	45 (9/20)	15 (3/20)	4.6 (1.1, 20)	p = 0.04‡

^†Determined by Fisher’s exact test. ^‡Determined by logistic regression models. Indel; insertion or deletion leading to an out-of-frame shift.