Table 3.

Odds ratios (95% CIs) of hearing loss by pack-years of smoking.

Pack-years of smoking #	N	Model 1*	Model 2 †	Model 3 ‡
Total
0	7484	ref	ref	ref
0 ~ <25	1501	2.05(1.82–2.32)	1.33(1.14–1.55)	1.29(1.10–1.51)
≥25	1717	2.36(2.10–2.66)	1.46(1.25–1.70)	1.42(1.21–1.66)
Sex
Male
0	1600	ref	ref	ref
0 ~ <25	1372	1.04(0.89–1.22)	1.25(1.06–1.48)	1.22(1.02–1.45)
≥25	1666	1.18(1.01–1.38)	1.40(1.19–1.65)	1.37(1.16–1.62)
Female
0	5884	ref	ref	ref
0 ~ <25	129	2.10(1.44–3.06)	1.57(1.04–2.36)	1.54(1.02–2.33)
≥25	51	2.68(1.42–5.05)	1.43(0.71–2.88)	1.42(0.71–2.84)
Age Group, y
<60
0	1610	ref	ref	ref
0~ <25	88	1.94(1.26–2.99)	2.11(1.20–3.70)	2.00(1.13–3.54)
≥25	58	1.38(0.80–2.38)	1.54(0.76–3.11)	1.48(0.72–3.05)
60 ~ < 70
0	3517	ref	ref	ref
0 ~ <25	798	1.84(1.56–2.16)	1.15(0.94–1.41)	1.15(0.93–1.42)
≥25	946	2.07(1.78–2.42)	1.26(1.03–1.54)	1.26(1.03–1.55)
≥70
0	2357	ref	ref	ref
0~ <25	615	1.30(1.03–1.63)	1.27(0.99–1.64)	1.22(0.94–1.58)
≥25	713	1.53(1.22–1.93)	1.51(1.17–1.94)	1.45(1.11–1.88)

^*Unadjusted.

^†Adjusted for age/sex.

^‡Adjusted for age/sex, race, shift work, occupational noise exposure, drinking status, hypertension, ototoxicity medicine, chronic diseases (diabetes mellitus, coronary heart disease, myocardial infarction and stroke).

^#The sample sizes vary slightly because of missing data.