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. 2017 Sep 11;7:11219. doi: 10.1038/s41598-017-11636-9

Table 1.

Characteristics of the study population (n = 1243).

Characteristic Control (n = 410)a Case Group I (n = 191)b Case Group II (n = 642)c Subgroup I (n = 122)d Subgroup II (n = 340)e Subgroup III (n = 311)f Subgroup IV (n = 611)g
Age (mean ± SD) 29.90 ± 3.61 29.19 ± 3.91 29.11 ± 4.51 29.39 ± 4.86 29.15 ± 4.54 29.11 ± 4.59 29.13 ± 4.45
BMI (mean ± SD)h 23.77 ± 2.94 23.23 ± 2.92 23.27 ± 3.11 23.48 ± 3.13 23.14 ± 3.11 23.12 ± 3.12 23.26 ± 3.14
Smoking status [n (%)]
   Never smoker 186 (45.4) 84 (44.0) 305 (47.5) 48 (39.3) 142 (41.8) 127 (40.8) 294 (48.1)
   Ever smoker 224 (54.6) 107 (56.0) 337 (52.5) 74 (60.7) 198 (58.2) 184 (59.2) 317 (51.9)
     Current smoker 199 (48.5) 90 (47.1) 288 (44.9) 66 (54.1) 169 (49.7) 155 (49.8) 268 (43.9)
     Former smoker 25 (6.1) 17 (8.9) 49 (7.6) 8 (6.6) 29 (8.5) 29 (9.3) 49 (8.0)
Pack-years (mean ± SD)f 4.58 ± 4.70 5.28 ± 4.15 5.33 ± 5.80 5.92 ± 7.79 5.30 ± 6.04 5.43 ± 6.23 5.25 ± 5.81
Drinking status [n (%)]
   Never drinker 187 (45.6) 99 (51.8) 290 (45.2) 56 (45.9) 148 (43.8) 137 (44.1) 274 (44.8)
   Ever drinker 223 (54.4) 92 (48.2) 387 (60.3) 66 (54.1) 192 (56.5) 174 (55.9) 337 (55.2)
      Current drinker 211 (51.5) 74 (38.7) 292 (45.5) 53 (43.3) 163 (47.9) 147 (47.3) 280 (45.8)
      Former drinker 12 (2.9) 18 (9.4) 95 (14.8) 13 (10.7) 29 (8.5) 27 (8.7) 57 (9.3)

SD, standard deviation; BMI, body mass index.

aProven fertility men with semen volume ≥ 2 ml, sperm concentration ≥20 × 106/ml, sperm number per ejaculum ≥40 × 106/ml and sperm motility ≥50% motile sperm.

bIdiopathic infertile men with all four semen parameters at or above the WHO reference value.

cIdiopathic infertile men with at least one of the abnormal semen parameters (semen volume, sperm concentration, sperm number per ejaculum and sperm motility).

dIdiopathic infertile men with semen volume < 2 ml.

eIdiopathic infertile men with sperm concentration <20 × 106/ml.

fIdiopathic infertile men with sperm number per ejaculum <40 × 106/ml.

gIdiopathic infertile men with sperm motility <50% motile sperm.

hBMI: kg/m2.