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. 2017 Sep 11;7:11141. doi: 10.1038/s41598-017-11747-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Test-retest reliability of 1.25 mm isotropic voxel size DTI in inferior brain white matter tracts. Panels a–d show the Bland-Altman (BA) plots for FA, AD, RD, and MD from one of the participants including the 95% confidence interval for the agreement between scan and repeat scan. Each symbol represents a white matter region of interest from the DTI Studio parcellation. The orange triangles in the BA plot show the agreement between scans in the OF and TP. The OF included the left and right lateral fronto-orbital gryus [LFOG] and middle fronto-orbital gyrus [MFOG] DTI Studio parcellation tracts, while the TP included the left and right superior temporal gyrus (STG), middle temporal gyrus [MTG], and inferior temporal gyrus [ITG]. Panels e–h show the difference in coefficient of variations (CoVs) for FA, AD, MD, and RD between controls and TBI as well as the overall mean CoV for each diffusion tensor metric and the mean CoVs for TP and OF. Panels i–l show the linear relationships including the 95% confidence interval band between the FA, AD, MD, and RD and atlas-based white matter tract z-axis centers for one of the participants. Panels m–p show the slopes of the relationship between z-axis centers and test-retest differences. Panels q–t show the R²s including standard deviation for the linear relationships between the FA, AD, MD, and RD and atlas-based white matter tract z-axis centers for controls and TBI separately. Abbreviations: FA, fractional anisotropy; AD, axial diffusivity; MD, mean diffusivity; RD, radial diffusivity; TBI; traumatic brain injury; OF, orbitofrontal; TP, temporal pole.