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. 2017 Sep 11;7:11110. doi: 10.1038/s41598-017-11709-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Kaplan-Meier cancer-free survival curves in the exploratory series of 82 patients with laryngeal dysplasias categorized by NANOG protein scores (A) or NANOG protein expression dichotomized as strong (score 2) versus negative to moderate expression (scores 0–1) (B). Kaplan-Meier cancer-free survival curves in the validation series of 86 patients with laryngeal dysplasias categorized by NANOG protein scores (C) or NANOG protein expression dichotomized as strong (score 2) versus negative to moderate expression (scores 0–1) (D). P values were estimated using the log-rank test.