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. 2017 Sep 11;36:74. doi: 10.1186/s40880-017-0241-4

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Flowchart of patients with cancer-related pain who were randomized to receive either controlled-release oxycodone/naloxone (OXN-CR) or controlled-release oxycodone (OX-CR). ^aThe patient was found to have significant structural/functional abnormalities of the gastrointestinal tract which was deemed to be not appropriate for oral medicine administration