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. 2017 Sep 11;14:36. doi: 10.1186/s12989-017-0217-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — In vitro IL-1β release and cytotoxicity in AM treated with silica ± imipramine. AM treatment conditions include IMP for 30 min, followed by exposure to LPS and silica for 24 h. a IL-1β release was measured by ELISA. b MTS assay results are expressed as cell viability relative to no silica, no IMP control. n ≥ 3 mice per treatment condition