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. Author manuscript; available in PMC: 2017 Sep 12.
Published in final edited form as: J Immunol. 2015 Nov 18;196(1):437–447. doi: 10.4049/jimmunol.1501529

Figure 6. Human caspase-12 dampens metabolic inflammation.

Figure 6

Subjects carrying the risk allele for the T125C SNP showed lower CRP (A–C) and IL-6 (D–F) levels than the non-carriers. This phenomenon seemed to be more marked in males than in females. In the subgroup of subjects who underwent an adipose tissue biopsy, the risk allele was associated with a lower percent of macrophages, and a lower expression of CD68, IL-6 and TNF-alpha (G–I).