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. 2017 Aug 22;114(36):E7460–E7468. doi: 10.1073/pnas.1620179114

Fig. 3.

Fig. 3.

Some HP foldamers have hydrophobic patches, which serve as landing pads that can catalyze the elongation of other HP chains. Chain A folds and exposes a hydrophobic sticky spot, or landing pad, where another HP molecule B as well as a hydrophobic monomer C can bind. This localization reduces the barrier for adding monomer C to the hydrophobic end of the growing chain B.