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Apoptosis induction for venetoclax combinations in AML cell lines. Three human AML cell lines (MOLM13, HL-60, and OCI-AML2) were cultured in the presence of venetoclax alone or in combination with doramapimod, ruxolitinib, idelalisib, or trametinib. All drug concentrations used were 50 nM. After 48 h, the percentage of cells positive for annexin V staining were measured by Guava Nexin assay (Millipore). Bars indicate the mean of three replicates ± SD.
