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Non-cumulative food (A) and ethanol consumption (B) in the SP and BEP groups over two 2-h intervals after NAc administration of the selective melanocortin 4 receptor (MC4-R) agonist cyclo(NH-CH2-CH2-CO-His-D-Phe-Arg-Trp-Glu)-NH2 (0, 0.75 μg or 1.5 μg). Administration of the selective agonist significantly decreased food and ethanol consumption relative to saline administration in both the SP and BEP groups. All values are means ± SEM.
