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. Author manuscript; available in PMC: 2017 Sep 12.
Published in final edited form as: Nat Commun. 2013;4:2959. doi: 10.1038/ncomms3959

Figure 3. Parathyroid-derived cervical thymus support atypical T cell development.

Figure 3

(a) Flow cytometric analysis of thoracic and cervical thymus at postnatal day 3 for CD4, CD8, CD25 and CD44 shows changes in the frequency of thymocyte subsets in cervical thymi (N>3). (b) Two classes of cervical thymi with either very low CD25 and TCRβ expression, or levels similar to thoracic thymus (N>3). Positive gates are indicated. (c) Ratio of CD4/CD8 is lower in parathyroid-derived cervical thymus, but shows variety in non-parathyroid derived cervical thymus, either similar/higher (CT#1, in red) or lower (CT#2, in blue) compared to thoracic thymus (N>3, Error bars represent SEM,). (d) Percentage of CD25+ cells is significantly lower in pCT, but is significantly higher in the CT#2 group of non-parathyroid derived cervical thymus (N>3; Error bars represent SEM, *significant relative to NB, t-Test, p<0.01 †significant relative to 28day, t-Test, p<0.01 ).