Table 4.
Baseline | 2years | 4 years | ||||||||||
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Without konzo | With konzo | p value | SMD | Without konzo | With konzo | p value | SMD | Without konzo | With konzo | p value | SMD | |
Mental processing index | 64·13 (61·68–66·68) | 61·04 (58·87–63·28) | 0·06 | 0·34 | 60·07 (56·98–63·32) | 55·08 (52·90–57·34) | 0·0111 | 0·56 | 60·74 (57·12–64·58) | 57·23 (54·48–60·13) | 0·11 | 0·39 |
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Sequential processing | 75·23 (71·94–78·66) | 72·86 (69·91–75·95) | 0·29 | 0·18 | 69·56 (65·52–73·85) | 65·56 (62·62–68·63) | 0·12 | 0·31 | 74·17 (69·19–79·52) | 69·35 (65·61–73·31) | 0·11 | 0·37 |
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Simultaneous processing | 69·17 (65·52–73·01) | 64·73 (61·58–68·04) | 0·08 | 0·41 | 64·28 (59·75–69·15) | 61·14 (57·81–64·65) | 0·28 | 0·29 | 67·17 (61·38–73·51) | 64·03 (59·47–68·94) | 0·39 | 0·29 |
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Learning | 70·48 (67·33–73·79) | 69·75 (66·84–72·78) | 0·74 | 0·07 | 69·78 (66·84–72·78) | 64·40 (61·45–67·50) | 0·0424 | 0·52 | 66·16 (61·60–71·04) | 65·60 (61·97–69·44) | 0·84 | 0·05 |
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Planning | 61·53 (58·74–64·46) | 56·19 (53·81–58·69) | 0·0056 | 0·48 | 57·41 (54·24–60·76) | 55·07 (52·63–57·62) | 0·26 | 0·21 | 59·06 (55·36–63·01) | 55·98 (53·00–59·13) | 0·20 | 0·28 |
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Delayed recall | 73·01 (70·09–76·05) | 74·47 (71·71–77·33) | 0·47 | 0·06 | 70·28 (66·39, 74·41) | 69·32 (66·46, 72·31) | 0·70 | 0·10 | 70·57 (65·88–75·59) | 68·45 (64·88–72·23) | 0·47 | 0·23 |
Data are means adjusted for child’s age and Caldwell HOME scale quality of caregiving environment, presented with 95% CI below the adjusted mean and SMDs after the p value of the ANCOVA between-group comparison. HOME=Home Observation for the Measurement of the Environment. KABC-II=Kaufman Assessment Battery for Children, second edition. SMD=standardised mean differences.