Table 1.
Clinicopathological characteristics in relation to CXCR4 and CXCR7 expression status
| Variable | Entire group (n=92) | CXCR4 | P value | CXCR7 | P value | ||
|---|---|---|---|---|---|---|---|
| Low | High | Low | High | ||||
| Age, years | 68 (35~87) | 0.799 | 0.983 | ||||
| <70 | 48(52.2) | 36 | 12 | 37 | 11 | ||
| ≥70 | 44(47.8) | 34 | 10 | 34 | 10 | ||
| Delay in diagnosis, months | 36 (2~244) | 0.575 | 0.071 | ||||
| <24 | 29(31.5) | 21 | 8 | 19 | 10 | ||
| ≥24 | 63(68.5) | 49 | 14 | 52 | 11 | ||
| Longest diameter of lesion, cm | 5 (1~12) | 0.815 | 0.634 | ||||
| <5 | 44(47.8) | 33 | 11 | 33 | 11 | ||
| ≥5 | 48(52.2) | 37 | 11 | 38 | 10 | ||
| Surgical margin status | 0.851 | 0.946 | |||||
| Positive | 18(19.6) | 14 | 4 | 14 | 4 | ||
| Negative | 74(80.4) | 56 | 18 | 57 | 17 | ||
| Depth of invasion | 0.318 | 0.010 | |||||
| Intraepithelial | 45(48.9) | 36 | 9 | 40 | 5 | ||
| Upper dermis | 21(22.8) | 17 | 4 | 16 | 5 | ||
| Lower dermis | 26(28.3) | 17 | 9 | 15 | 11 | ||
| Lymphovascular invasion | 0.007 | 0.000 | |||||
| Yes | 16(17.4) | 8 | 8 | 7 | 9 | ||
| No | 76(82.6) | 62 | 14 | 64 | 12 | ||
| Regional lymph node metastasis at diagnosis | 0.037 | 0.025 | |||||
| Yes | 19(20.7) | 11 | 8 | 11 | 8 | ||
| No | 73(79.3) | 59 | 14 | 60 | 13 | ||