Table 4.

Sensitivity and specificity after integrating prostate size and history of prior biopsy into the biomarkers algorithm and analyzing the group with high proportion of non-aggressive patient in a separate algorithm (Logistic 1) and the group with the high proportion of aggressive patients in a second algorithm (Logistic 2). The sensitivity of specificity at various cut-off points are shown.

		Logistic 2
Logistic 1	Sensitivity	0.10	0.15	0.20	0.25	0.30
	0.10	0.973	0.952	0.946	0.925	0.905
	0.15	0.946	0.925	0.918	0.898	0.878
	0.20	0.912	0.891	0.884	0.864	0.844
	0.25	0.878	0.857	0.850	0.830	0.810
	0.30	0.857	0.837	0.830	0.810	0.789
		Logistic 2
Logistic 1	Specificity	0.10	0.15	0.20	0.25	0.30
	0.10	0.363	0.377	0.401	0.447	0.465
	0.15	0.442	0.456	0.480	0.526	0.544
	0.20	0.506	0.520	0.544	0.591	0.608
	0.25	0.544	0.558	0.582	0.629	0.646
	0.30	0.570	0.585	0.608	0.655	0.673