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. 2017 Aug 21;8(13):2643–2652. doi: 10.7150/jca.20234

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© Ivyspring International Publisher

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.

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The BAP1 mutation-specific miRNA risk score analysis of ccRCC patients with wild-type BAP1. A. miRNA risk score distribution; B. Patients' survival status and time; C. Heatmap of the miRNA expression profiles; rows represented miRNAs, and columns indicated patients. The red dotted line represented the miRNA signature cutoff value (median), which divided patients into low-risk and high-risk groups. D. Kaplan-Meier curve analysis of the miRNA signature for the overall survival in 315 ccRCC patients with wild-type BAP1.