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In vitro bifunctionality of Tand-scFvSca-1+GPIIb/IIIa and Tand-scFvSca-1+Mutant. Tand-scFvSca-1+GPIIb/IIIa specifically increases adhesion of Sca-1-expressing HEK cells to a monolayer of ADP activated human platelets under A) static and B) physiological flow conditions (fov = field of view, n=3). Representative images show adhering Sca-1-expressing HEK cells (magnification: 400x (A) and 200x (B), scale bar: 50 µm (A) and 100 µm (B)). Data are represented as mean ± SD.
